Publications

Crystal structures and mutagenesis of PPP-family ser/thr protein phosphatases elucidate the selectivity of cantharidin and novel norcantharidin-based inhibitors of PP5C.

Chattopadhyay D, Swingle MR, Salter EA, Wood E, D’Arcy B, Zivanov C, Abney K, Musiyenko A, Rusin SF, Kettenbach A, Yet L, Schroeder CE, Golden JE, Dunham WH, Gingras AC, Banerjee S, Forbes D, Wierzbicki A, Honkanen RE. pubmed

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Neurospora WC-1 recruits SWI/SNF to remodel frequency and initiate a circadian cycle.

Neurospora WC-1 recruits SWI/SNF to remodel frequency and initiate a circadian cycle. Wang B, Kettenbach AN, Gerber SA, Loros JJ, Dunlap JC. PLoS Genetics. Sep 25;10(9):e1004599. doi: 10.1371/journal.pgen.1004599. pubmed

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Dueling kinases regulate cell size at division through the SAD kinase Cdr2.

Dueling kinases regulate cell size at division through the SAD kinase Cdr2. Deng L, Baldissard S, Kettenbach AN, Gerber SA, Moseley JB. Current Biology.  Feb 17;24(4):428-33. doi: 10.1016/j.cub.2014.01.009. Epub 2014 Feb 6. pubmed  

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Structures of Down syndrome kinases, DYRKs, reveal mechanisms of kinase activation and substrate recognition.

Structures of Down syndrome kinases, DYRKs, reveal mechanisms of kinase activation and substrate recognition. Soundararajan M, Roos AK, Savitsky P, Filippakopoulos P, Kettenbach AN, Olsen JV, Gerber SA, Eswaran J, Knapp S, Elkins JM. Structure. 2013 Jun 4;21(6):986-96. doi: 10.1016/j.str.2013.03.012. Epub 2013 May 9. [pubmed]

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Akt Regulates TNFα synthesis downstream of RIP1 kinase activation during necroptosis.

Akt Regulates TNFα synthesis downstream of RIP1 kinase activation during necroptosis. McNamara CR, Ahuja R, Osafo-Addo AD, Barrows D, Kettenbach AN, Skidan I, Teng X, Cuny GD, Gerber S, Degterev A. PLoS One. 2013;8(3):e56576. doi: 10.1371/journal.pone.0056576. Epub 2013 Mar 1. [pubmed]

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Rapid determination of multiple linear kinase substrate motifs by mass spectrometry.

Rapid determination of multiple linear kinase substrate motifs by mass spectrometry.
 Kettenbach AN, Wang T, Faherty BK, Madden DR, Knapp S, Bailey-Kellogg C, Gerber SA.
Chem Biol. 2012 May 25;19(5):608-18. doi: 10.1016/j.chembiol.2012.04.011. [pubmed]

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Plk1 regulates the kinesin-13 protein Kif2b to promote faithful chromosome segregation.

Plk1 regulates the kinesin-13 protein Kif2b to promote faithful chromosome segregation.
Hood EA, Kettenbach AN, Gerber SA, Compton DA.
Mol Biol Cell. 2012 Jun; 23(12):2264-74. doi: 10.1091/mbc.E11-12-1013. Epub 2012 Apr 25. [pubmed]

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MMFPh: a maximal motif finder for phosphoproteomics datasets.

MMFPh: a maximal motif finder for phosphoproteomics datasets.
 Wang T, Kettenbach AN, Gerber SA, Bailey-Kellogg C.
Bioinformatics. 2012 Jun 15;28(12):1562-70. doi: 10.1093/bioinformatics/bts195. Epub 2012 Apr 23. [pubmed]

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Increasing phosphoproteomic coverage through sequential digestion by complementary proteases.

Increasing phosphoproteomic coverage through sequential digestion by complementary proteases. Gilmore JM, Kettenbach AN, Gerber SA. Anal Bioanal Chem. 2012 Jan; 402(2):711-20. doi: 10.1007/s00216-011-5466-5. Epub 2011 Oct 15. [pubmed]

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Rapid and reproducible single-stage phosphopeptide enrichment of complex peptide mixtures: application to general and phosphotyrosine-specific phosphoproteomics experiments.

Rapid and reproducible single-stage phosphopeptide enrichment of complex peptide mixtures: application to general and phosphotyrosine-specific phosphoproteomics experiments. Kettenbach AN, Gerber SA. Anal Chem. 2011 Oct 15;83(20):7635-44. doi: 10.1021/ac201894j. Epub 2011 Sep 20. [pubmed]

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