Increasing phosphoproteomic coverage through sequential digestion by complementary proteases.

Increasing phosphoproteomic coverage through sequential digestion by complementary proteases. Gilmore JM, Kettenbach AN, Gerber SA. Anal Bioanal Chem. 2012 Jan; 402(2):711-20. doi: 10.1007/s00216-011-5466-5. Epub 2011 Oct 15. [pubmed]

Rapid and reproducible single-stage phosphopeptide enrichment of complex peptide mixtures: application to general and phosphotyrosine-specific phosphoproteomics experiments.

Rapid and reproducible single-stage phosphopeptide enrichment of complex peptide mixtures: application to general and phosphotyrosine-specific phosphoproteomics experiments. Kettenbach AN, Gerber SA. Anal Chem. 2011 Oct 15;83(20):7635-44. doi: 10.1021/ac201894j. Epub 2011 Sep 20. [pubmed]

Proteomic analysis shows synthetic oleanane triterpenoid binds to mTOR.

Proteomic analysis shows synthetic oleanane triterpenoid binds to mTOR.
Yore MM, Kettenbach AN, Sporn MB, Gerber SA, Liby KT.
PLoS One. 2011;6(7):e22862. doi: 10.1371/journal.pone.0022862. Epub 2011 Jul 27. [pubmed]

Quantitative phosphoproteomics identifies substrates and functional modules of Aurora and Polo-like kinase activities in mitotic cells.

Quantitative phosphoproteomics identifies substrates and functional modules of Aurora and Polo-like kinase activities in mitotic cells. Kettenbach AN, Schweppe DK, Faherty BK, Pechenick D, Pletnev AA, Gerber SA. Sci Signal. 2011 Jun 28;4(179):rs5. doi: 10.1126/scisignal.2001497. [pubmed]

Insulin-stimulated GLUT4 protein translocation in adipocytes requires the Rab10 guanine nucleotide exchange factor Dennd4C.

Insulin-stimulated GLUT4 protein translocation in adipocytes requires the Rab10 guanine nucleotide exchange factor Dennd4C. Sano H, Peck GR, Kettenbach AN, Gerber SA, Lienhard GE. J Biol Chem. 2011 May 13; 286(19):16541-5. doi: 10.1074/jbc.C111.228908. Epub 2011 Mar 22. [pubmed]

Absolute quantification of protein and post-translational modification abundance with stable isotope-labeled synthetic peptides.

Absolute quantification of protein and post-translational modification abundance with stable isotope-labeled synthetic peptides. Kettenbach AN, Rush J, Gerber SA. Nat Protoc. 2011 Feb; 6(2):175-86. doi: 10.1038/nprot.2010.196. Epub 2011 Jan 27. [pubmed]